As a major focus of REACH regulation, the candidate list of Substances of Very High Concern (SVHC) has undergone several updates since the entry into force of REACH regulation.

If an article contains any SVHC (concentration above 0.1%(w/w)) included in the Candidate List, the EU manufacturer or importer shall fulfil the obligations of notification and provide sufficient information on request to consumers within 45 days upon the receipt of this request.  Any articles imported to EU with >0.1% SVHC Candidate List substance shall submit a notification to the SCIP Database as per the Waste Framework Directive amendment (EU) 2018/851.Suppliers must notify ECHA about the SVHC in products if the concentration of a SVHC is above 0.1% (w/w) and the import quantity is above 1 tonne / year. Suppliers of substance or mixture have to provide a safety data sheet (SDS) to their downstream users.

The European Chemicals Agency (ECHA) held a public consultation over the inclusion of N-(hydroxymethyl)acrylamide and on 10 June 2022, it had been officially included to the Candidate List, hence expanding the total number of substances to 224.

Table 1. 27^th SVHC Candidate List Substance and its common application